Rbm14^em1Wli
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rbm14^em1Wli
• Name: RNA binding motif protein 14; endonuclease-mediated mutation 1, Wei Li
• MGI ID: MGI:6455488
• Gene: Rbm14 Location: Chr19:4850597-4861662 bp, - strand Genetic Position: Chr19, 4.11 cM, cytoband A
• Alliance: Rbm14^em1Wli page

Mutation origin

• Strain of Origin: ICR

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting of exon 1 deleted 68 bp causing a frame shift and premature termination at the N-terminus. (J:290444)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbm14 Mutation: 70 strains or lines available

References

• Original: J:290444 Li J, et al., Rbm14 maintains the integrity of genomic DNA during early mouse embryogenesis via mediating alternative splicing. Cell Prolif. 2020 Jan;53(1):e12724
• All: 1 reference(s)