Tg(tetO-flpo)1Bbd
Transgene Detail

Summary

• Symbol: Tg(tetO-flpo)1Bbd
• Name: transgene insertion 1, Mariano Barbacid
• MGI ID: MGI:6455673
• Synonyms: TetO-FlpO
• Transgene: Tg(tetO-flpo)1Bbd Location: unknown
• Alliance: Tg(tetO-flpo)1Bbd page

Transgene origin

• Strain of Origin: C57BL/6 x CBA

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-flpo)1Bbd expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  bacteria	tetO

• Mutation details: The expression of a codon-optimized Flp recombinase (Flpo) is driven by an inducible tetracycline response element and minimal promoter. (J:274213)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	tetO (bacteria) Summary of all recombinase alleles driven by tetO.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:274213 Blasco MT, et al., Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF. Cancer Cell. 2019 Apr 15;35(4):573-587.e6
• All: 2 reference(s)