Mir149^em1Ydw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mir149^em1Ydw
• Name: microRNA 149; endonuclease-mediated mutation 1, Yan-Dong Wang
• MGI ID: MGI:6455680
• Synonyms: miR-149*^-
• Gene: Mir149 Location: Chr1:92778100-92778165 bp, + strand Genetic Position: Chr1, 46.6 cM
• Alliance: Mir149^em1Ydw page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 19 bp. (J:294318)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir149 Mutation: 2 strains or lines available

References

• Original: J:294318 Zhang Q, et al., MicroRNA-149* suppresses hepatic inflammatory response through antagonizing STAT3 signaling pathway. Oncotarget. 2017;8(39):65397-65406
• All: 2 reference(s)