Rnase1^tm1.2Rtrs
Targeted Allele Detail

Summary

• Symbol: Rnase1^tm1.2Rtrs
• Name: ribonuclease, RNase A family, 1 (pancreatic); targeted mutation 1.2, Ronald T Raines
• MGI ID: MGI:6456551
• Gene: Rnase1 Location: Chr14:51382459-51384224 bp, - strand Genetic Position: Chr14, 26.4 cM, cytoband B-C1
• Alliance: Rnase1^tm1.2Rtrs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:288762
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding region was floxed. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed the entire coding region. (J:288762)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnase1 Mutation: 9 strains or lines available

References

• Original: J:288762 Garnett ER, et al., Phenotype of ribonuclease 1 deficiency in mice. RNA. 2019 Aug;25(8):921-934
• All: 1 reference(s)