Opn3^em1(cre)Lan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Opn3^em1(cre)Lan
• Name: opsin 3; endonuclease-mediated mutation 1, Richard A Lang
• MGI ID: MGI:6456884
• Synonyms: Opn3^cre
• Gene: Opn3 Location: Chr1:175489987-175520198 bp, - strand Genetic Position: Chr1, 81.66 cM, cytoband H3
• Alliance: Opn3^em1(cre)Lan page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Opn3^em1(cre)Lan expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Opn3 (MGI:1338022)

• CRISPR-targeting inserted the cre recombinase gene. (J:287419)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Opn3 (mouse) Summary of all recombinase alleles driven by Opn3. Comparative matrix view of recombinase activities Alliance mouse Opn3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Opn3 Mutation: 23 strains or lines available

References

• Original: J:287419 Nayak G, et al., Adaptive Thermogenesis in Mice Is Enhanced by Opsin 3-Dependent Adipocyte Light Sensing. Cell Rep. 2020 Jan 21;30(3):672-686.e8
• All: 1 reference(s)