Rer1^{Gt(EUCJ0172c09)1.1Hmgu}
Gene trapped Allele Detail

Summary

• Symbol: Rer1^{Gt(EUCJ0172c09)1.1Hmgu}
• Name: retention in endoplasmic reticulum sorting receptor 1; gene trap 1.1, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:6457373
• Synonyms: Rer1^trap
• Gene: Rer1 Location: Chr4:155158567-155170839 bp, - strand Genetic Position: Chr4, 86.17 cM
• Alliance: Rer1^{Gt(EUCJ0172c09)1.1Hmgu} page

Mutation origin

• Mutant Cell Line: EUCJ0172c09
• Germline Transmission: Earliest citation of germline transmission: J:266159
• Parent Cell Line: JM8 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Conditional ready, No functional change)
• Mutation: Insertion of gene trap vector Vector: FlipROSAbetageo
• Mutation details: The gene trap vector, which consists of splice acceptor site linked to a beta-geo selectable marker, was inserted into the 1st intron of the Rer1 gene on chromosome 4. Exon 2 encodes the translation initiation codon of the Rer1 protein. Flp-mediated recombination inverted the gene trap to produce a conditional allele. (J:266159)

Expression

In Mice Carrying this Mutation:

86 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rer1 Mutation: 29 strains or lines available

References

• Original: J:266159 Hara T, et al., Rer1-mediated quality control system is required for neural stem cell maintenance during cerebral cortex development. PLoS Genet. 2018 Sep;14(9):e1007647
• All: 1 reference(s)