Atxn2l^em1Aub
Endonuclease-mediated Allele Detail

Summary

• Symbol: Atxn2l^em1Aub
• Name: ataxin 2-like; endonuclease-mediated mutation 1, Georg Auburger
• MGI ID: MGI:6458736
• Gene: Atxn2l Location: Chr7:126090880-126102609 bp, - strand Genetic Position: Chr7, 69.09 cM
• Alliance: Atxn2l^em1Aub page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting deleted exons 5 through 8. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts. (J:294770)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atxn2l Mutation: 44 strains or lines available

References

• Original: J:294770 Key J, et al., Mid-Gestation lethality of Atxn2l-Ablated Mice. Int J Mol Sci. 2020 Jul 20;21(14):5124
• All: 1 reference(s)