Clrn2^em1H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Clrn2^em1H
• Name: clarin 2; endonuclease-mediated mutation 1, Harwell
• MGI ID: MGI:6458758
• Synonyms: Clrn2^del629
• Gene: Clrn2 Location: Chr5:45611093-45621491 bp, + strand Genetic Position: Chr5, Syntenic
• Alliance: Clrn2^em1H page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 629 bp of exon 2. (J:283627)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Clrn2 Mutation: 26 strains or lines available

References

• Original: J:283627 Dunbar LA, et al., Clarin-2 is essential for hearing by maintaining stereocilia integrity and function. EMBO Mol Med. 2019 Sep;11(9):e10288
• All: 2 reference(s)