Prdx1^tm1Yu
Targeted Allele Detail

Summary

• Symbol: Prdx1^tm1Yu
• Name: peroxiredoxin 1; targeted mutation 1, Dae-Yeul Yu
• MGI ID: MGI:6458773
• Synonyms: Prx I^-
• Gene: Prdx1 Location: Chr4:116542796-116557196 bp, + strand Genetic Position: Chr4, 53.28 cM
• Alliance: Prdx1^tm1Yu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:294784
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• All coding exons (1-6) were replaced with a neomycin selection gene. (J:294784)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdx1 Mutation: 39 strains or lines available

References

• Original: J:294784 Han YH, et al., Peroxiredoxin I deficiency attenuates phagocytic capacity of macrophage in clearance of the red blood cells damaged by oxidative stress. BMB Rep. 2012 Oct;45(10):560-4
• All: 15 reference(s)