Vps4b^tm1Thkn
Targeted Allele Detail

Summary

• Symbol: Vps4b^tm1Thkn
• Name: vacuolar protein sorting 4B; targeted mutation 1, Thomas Klein
• MGI ID: MGI:6459255
• Gene: Vps4b Location: Chr1:106698518-106724455 bp, - strand Genetic Position: Chr1, 50.1 cM, cytoband D
• Alliance: Vps4b^tm1Thkn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:236761
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced exons 1 through 4. (J:236761)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vps4b Mutation: 21 strains or lines available

References

• Original: J:236761 Drusenheimer N, et al., The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling. PLoS Genet. 2015 Dec;11(12):e1005749
• All: 1 reference(s)