Lelp1^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lelp1^em1Osb
• Name: late cornified envelope-like proline-rich 1; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6459762
• Gene: Lelp1 Location: Chr3:92042304-92050051 bp, - strand Genetic Position: Chr3, 40.14 cM, cytoband F2
• Alliance: Lelp1^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• CRISPR-targeting deleted 577 bp and added 118 bp. (J:293870)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Lelp1 Mutation: 10 strains or lines available

References

• Original: J:293870 Sun J, et al., CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction. Biol Reprod. 2020 Aug 4;103(2):183-194
• All: 1 reference(s)