Brme1^em1Zhal
Endonuclease-mediated Allele Detail

Summary

• Symbol: Brme1^em1Zhal
• Name: break repair meiotic recombinase recruitment factor 1; endonuclease-mediated mutation 1, Liangran Zhang
• MGI ID: MGI:6460292
• Gene: Brme1 Location: Chr8:84874654-84899219 bp, + strand Genetic Position: Chr8, 40.35 cM, cytoband C3
• Alliance: Brme1^em1Zhal page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-cas9 mediated recombination removed a 9126 bp genomic region including exons 3 through 6. (J:291221)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Brme1 Mutation: 24 strains or lines available

References

• Original: J:291221 Shang Y, et al., MEIOK21: a new component of meiotic recombination bridges required for spermatogenesis. Nucleic Acids Res. 2020 Jul 9;48(12):6624-6639
• All: 2 reference(s)