Cfap206^tm1.2Gos
Targeted Allele Detail

Summary

• Symbol: Cfap206^tm1.2Gos
• Name: cilia and flagella associated protein 206; targeted mutation 1.2, Achim Gossler
• MGI ID: MGI:6466698
• Synonyms: Cfap206^{delta ex4}
• Gene: Cfap206 Location: Chr4:34688559-34730206 bp, - strand Genetic Position: Chr4, 16.86 cM
• Alliance: Cfap206^tm1.2Gos page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:293391
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 4. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 4. (J:293391)

Expression

In Mice Carrying this Mutation:	11 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cfap206 Mutation: 35 strains or lines available

References

• Original: J:293391 Beckers A, et al., The FOXJ1 target Cfap206 is required for sperm motility, mucociliary clearance of the airways and brain development. Development. 2020 Jun 15;147(21):dev188052
• All: 1 reference(s)