Gt(ROSA)26Sor^{tm4.1(CAG-dre)Ics}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm4.1(CAG-dre)Ics}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 4.1, Mouse Clinical Institute
• MGI ID: MGI:6467222
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm4.1(CAG-dre)Ics} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:296062
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm4.1(CAG-dre)Ics} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  chicken	CAG

• Mutation details: Constitutive ubiquitous expression of the Dre recombinase under the CAG promoter. Recombination removed the selection cassette. (J:296062)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	CAG (chicken) Summary of all recombinase alleles driven by CAG.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:296062 Birling M-C, Gt(ROSA)26Sor Dre recombinase allele. MGI Direct Data Submission. 2020
• All: 1 reference(s)