Spocd1^em1Doca
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spocd1^em1Doca
• Name: SPOC domain containing 1; endonuclease-mediated mutation 1, Donal O'Carroll
• MGI ID: MGI:6467407
• Synonyms: Spocd1^null
• Gene: Spocd1 Location: Chr4:129823042-129850908 bp, + strand Genetic Position: Chr4, 63.43 cM
• Alliance: Spocd1^em1Doca page

Mutation origin

• Strain of Origin: (C57BL/6J x CBA/CaCrl)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRIPSR/Cas9 genome editing technology was used to generate a 13bp deletion in exon 7. (J:295943)

Expression

In Mice Carrying this Mutation:	5 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spocd1 Mutation: 30 strains or lines available

References

• Original: J:295943 Zoch A, et al., SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation. Nature. 2020 Aug;584(7822):635-639
• All: 1 reference(s)