Sppl3^tm1Itl
Targeted Allele Detail

Summary

• Symbol: Sppl3^tm1Itl
• Name: signal peptide peptidase 3; targeted mutation 1, Ingenious Targeting Laboratory
• MGI ID: MGI:6467467
• Synonyms: SPPL3^fl
• Gene: Sppl3 Location: Chr5:115149204-115236849 bp, + strand Genetic Position: Chr5, 55.99 cM, cytoband F
• Alliance: Sppl3^tm1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:280182
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• LoxP sites were inserted to flank exon 3. (J:280182)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sppl3 Mutation: 75 strains or lines available

References

• Original: J:280182 Hamblet CE, et al., NK Cell Maturation and Cytotoxicity Are Controlled by the Intramembrane Aspartyl Protease SPPL3. J Immunol. 2016 Mar 15;196(6):2614-26
• All: 1 reference(s)