Spaca6^em1Nino
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spaca6^em1Nino
• Name: sperm acrosome associated 6; endonuclease-mediated mutation 1, Naokazu Inoue
• MGI ID: MGI:6467749
• Gene: Spaca6 Location: Chr17:18047420-18063271 bp, + strand Genetic Position: Chr17, 10.5 cM, cytoband A3.1
• Alliance: Spaca6^em1Nino page

Mutation origin

• Strain of Origin: C57BL/6 x DBA/2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 28 bp. (J:304712)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Spaca6 Mutation: 37 strains or lines available

References

• Original: J:304712 Inoue N, et al., Evolutionarily conserved sperm factors, DCST1 and DCST2, are required for gamete fusion. Elife. 2021 Apr 19;10:e66313
• All: 1 reference(s)