Impa1^Rgsc01846
Chemically induced Allele Detail

Summary

• Symbol: Impa1^Rgsc01846
• Name: inositol (myo)-1(or 4)-monophosphatase 1; RIKEN Genomic Sciences Center (GSC), 01846
• MGI ID: MGI:6469955
• Synonyms: Impa1^T95K
• Gene: Impa1 Location: Chr3:10377016-10396499 bp, - strand Genetic Position: Chr3, 2.61 cM
• Alliance: Impa1^Rgsc01846 page

Mutation origin

• Strain of Origin: C57BL/6JJcl
• Project Collection: RIKEN GSC ENU Project

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a C to A point mutation in exon 4 that results in the amino acid substitution of threonine to lysine at position 95 (T95K). (J:250420)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Impa1 Mutation: 22 strains or lines available

References

• Original: J:250420 Ohnishi T, et al., Defective craniofacial development and brain function in a mouse model for depletion of intracellular inositol synthesis. J Biol Chem. 2014 Apr 11;289(15):10785-96
• All: 1 reference(s)