Impa2^Rgsc01362
Chemically induced Allele Detail

Summary

• Symbol: Impa2^Rgsc01362
• Name: inositol monophosphatase 2; RIKEN Genomic Sciences Center (GSC), 01362
• MGI ID: MGI:6469987
• Synonyms: Impa2^I282T
• Gene: Impa2 Location: Chr18:67422246-67454375 bp, + strand Genetic Position: Chr18, 39.92 cM
• Alliance: Impa2^Rgsc01362 page

Mutation origin

• Strain of Origin: C57BL/6JJcl
• Project Collection: RIKEN GSC ENU Project

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to C point mutation in exon 8 that produces the amino acid substitution of isoleucine with threonine at position 282 (I282T). (J:250420)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Impa2 Mutation: 27 strains or lines available

References

• Original: J:250420 Ohnishi T, et al., Defective craniofacial development and brain function in a mouse model for depletion of intracellular inositol synthesis. J Biol Chem. 2014 Apr 11;289(15):10785-96
• All: 1 reference(s)