Bcl2l14^tm1.1Boui
Targeted Allele Detail

Summary

• Symbol: Bcl2l14^tm1.1Boui
• Name: BCL2 like 14; targeted mutation 1.1, Philippe Bouillet
• MGI ID: MGI:6470550
• Synonyms: Bcl-G^-
• Gene: Bcl2l14 Location: Chr6:134373292-134415687 bp, + strand Genetic Position: Chr6, 65.22 cM
• Alliance: Bcl2l14^tm1.1Boui page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:243990
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The ATG-containing exon 3 was flanked by loxP sites. An FRT site, loxP site, hygromycin resistance selection cassette and FRT site were inserted upstream of the floxed exon 3. The hygromycin resistance cassette and exon 3 were deleted via cre-mediated recombination. (J:243990)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl2l14 Mutation: 20 strains or lines available

References

• Original: J:243990 Giam M, et al., Bcl-2 family member Bcl-G is not a proapoptotic protein. Cell Death Dis. 2012 Oct 11;3:e404
• All: 2 reference(s)