Pdx1^{tm4.1(cre)Mgn}
Targeted Allele Detail

Summary

• Symbol: Pdx1^{tm4.1(cre)Mgn}
• Name: pancreatic and duodenal homeobox 1; targeted mutation 4.1, Mark A Magnuson
• MGI ID: MGI:6470616
• Synonyms: Pdx1^creMgn
• Gene: Pdx1 Location: Chr5:147206907-147212658 bp, + strand Genetic Position: Chr5, 86.84 cM
• Alliance: Pdx1^{tm4.1(cre)Mgn} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:296396
• Parent Cell Line: TL1/TL-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Pdx1^{tm4.1(cre)Mgn} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pdx1 (MGI:102851)

• Mutation details: RMCE on the loxed cassette acceptor (LCA) allele inserted an exon1 with an inframe cre recombinase. The hygromycin resistance cassette was removed in the final allele. (J:296396)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pdx1 (mouse) Summary of all recombinase alleles driven by Pdx1. Alliance mouse Pdx1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pdx1 Mutation: 35 strains or lines available

References

• Original: J:296396 Vanderbilt University, Labnodes. 2020
• All: 1 reference(s)