Prl7d1^em1Liga
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prl7d1^em1Liga
• Name: prolactin family 7, subfamily d, member 1; endonuclease-mediated mutation 1, Gang Li
• MGI ID: MGI:6470966
• Gene: Prl7d1 Location: Chr13:27892981-27900720 bp, - strand Genetic Position: Chr13, 12.6 cM
• Alliance: Prl7d1^em1Liga page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: TALEN mediated recombination created an 11 bp deletion. Western blot analysis confirmed the absence of protein expression in placental extracts from homozygous mice. (J:288761)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prl7d1 Mutation: 31 strains or lines available

References

• Original: J:288761 Zhang Q, et al., Deletion of Prl7d1 causes placental defects at mid-pregnancy in mice. Mol Reprod Dev. 2019 Jun;86(6):696-713
• All: 1 reference(s)