Abhd11^tm1Esco
Targeted Allele Detail

Summary

• Symbol: Abhd11^tm1Esco
• Name: abhydrolase domain containing 11; targeted mutation 1, Johanna Escoubet
• MGI ID: MGI:6471012
• Gene: Abhd11 Location: Chr5:135038006-135041029 bp, + strand Genetic Position: Chr5, 74.94 cM
• Alliance: Abhd11^tm1Esco page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:294591
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding region was replaced with a lacZ-loxP-U-b1-em7-neo-loxP cassette. RT-PCR and western blot analysis confirmed the absence of expression in homozygous mice. (J:294591)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Abhd11 Mutation: 8 strains or lines available

Notes

ES cell line - C57BL/6F1

References

• Original: J:294591 Escoubet J, et al., ABHD11, a new diacylglycerol lipase involved in weight gain regulation. PLoS One. 2020;15(6):e0234780
• All: 1 reference(s)