Tg(Kiss1-cre,-AcGFP)1Nurep
Transgene Detail

Summary

• Symbol: Tg(Kiss1-cre,-AcGFP)1Nurep
• Name: transgene insertion 1, Lab of Reproductive Science
• MGI ID: MGI:6472634
• Synonyms: Kiss1-Cre-GFP (#1336)
• Transgene: Tg(Kiss1-cre,-AcGFP)1Nurep Location: unknown
• Alliance: Tg(Kiss1-cre,-AcGFP)1Nurep page

Transgene origin

• Strain of Origin: (C57BL/6J x DBA)F1

Transgene description

• Transgene Type: Transgenic (Recombinase, Reporter)
• Mutation: Insertion
• Tg(Kiss1-cre,-AcGFP)1Nurep expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Kiss1 (MGI:2663985)

• Mutation details: The transgene contains a genomic segment from BAC clone RP24-299J2 in which a cre recombinase gene, IRES sequence, and AcGFP reporter gene replaced exon 2. Line 1 and 2 were generated. (J:296176)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Kiss1 (mouse) Summary of all recombinase alleles driven by Kiss1. Comparative matrix view of recombinase activities Alliance mouse Kiss1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:296176 Ikegami K, et al., Conditional kisspeptin neuron-specific Kiss1 knockout with newly generated Kiss1-floxed and Kiss1-Cre mice replicates a hypogonadal phenotype of global Kiss1 knockout mice. J Reprod Dev. 2020 Aug 20;66(4):359-367
• All: 1 reference(s)