Cyp26c1^tm1Hmd
Targeted Allele Detail

Summary

• Symbol: Cyp26c1^tm1Hmd
• Name: cytochrome P450, family 26, subfamily c, polypeptide 1; targeted mutation 1, Hiroshi Hamada
• MGI ID: MGI:6473138
• Gene: Cyp26c1 Location: Chr19:37674029-37681846 bp, + strand Genetic Position: Chr19, 32.36 cM
• Alliance: Cyp26c1^tm1Hmd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:119939
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: B6;129-Cyp26a1^tm1.1Hmd/HmdRbrc

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct introduced upstream of exon 1 an FRT-flanked neomycin resistance cassette with a loxP site. (J:119939)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cyp26c1 Mutation: 23 strains or lines available

Notes

This allele was generated in ES cells containing Cyp26a1^tm1.1Hmd

References

• Original: J:119939 Uehara M, et al., CYP26A1 and CYP26C1 cooperatively regulate anterior-posterior patterning of the developing brain and the production of migratory cranial neural crest cells in the mouse. Dev Biol. 2007 Feb 15;302(2):399-411
• All: 1 reference(s)