Slc16a7^tm1.1Lupel
Targeted Allele Detail

Summary

• Symbol: Slc16a7^tm1.1Lupel
• Name: solute carrier family 16 (monocarboxylic acid transporters), member 7; targeted mutation 1.1, Luc Pellerin
• MGI ID: MGI:6473153
• Synonyms: MCT2^f
• Gene: Slc16a7 Location: Chr10:125055139-125225334 bp, - strand Genetic Position: Chr10, 72.31 cM, cytoband D3
• Alliance: Slc16a7^tm1.1Lupel page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:296969
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An FRT site flanked neomycin resistance gene cassette and a loxP site were inserted into intron 3 and a second loxP site into intron 5. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele with exon 4-5 floxed. (J:296969)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc16a7 Mutation: 29 strains or lines available

References

• Original: J:296969 Netzahualcoyotzi C, et al., Neuronal and astroglial monocarboxylate transporters play key but distinct roles in hippocampus-dependent learning and memory formation. Prog Neurobiol. 2020 Nov;194:101888
• All: 2 reference(s)