Ids^tm1Dkji
Targeted Allele Detail

Summary

• Symbol: Ids^tm1Dkji
• Name: iduronate 2-sulfatase; targeted mutation 1, Dong-Kyu Jin
• MGI ID: MGI:6474226
• Gene: Ids Location: ChrX:69386675-69408690 bp, - strand Genetic Position: ChrX, 36.01 cM
• Alliance: Ids^tm1Dkji page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:294717
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• 1485 bp encompassing exon 2 and 3 were replaced with a neomycin resistance gene. (J:294717)

Disease models

Expression

In Structures Affected by this Mutation:

13 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ids Mutation: 11 strains or lines available

References

• Original: J:294717 Jung SC, et al., Characterization of a novel mucopolysaccharidosis type II mouse model and recombinant AAV2/8 vector-mediated gene therapy. Mol Cells. 2010 Jul;30(1):13-8
• All: 2 reference(s)