Palmd^tm1.2Kili
Targeted Allele Detail

Summary

• Symbol: Palmd^tm1.2Kili
• Name: palmdelphin; targeted mutation 1.2, Manfred W Kilimann
• MGI ID: MGI:6477926
• Gene: Palmd Location: Chr3:116711907-116762636 bp, - strand Genetic Position: Chr3, 50.49 cM
• Alliance: Palmd^tm1.2Kili page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:320912
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 4 to 6 were flanked by loxP sites. A neomycin selection cassette was removed. Cre-mediated recombination deleted exons 4 to 6. (J:320912)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Palmd Mutation: 36 strains or lines available

Notes

ES cell = B-D6 (C57BL/6N)

References

• Original: J:320912 Sainz-Jaspeado M, et al., Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium. Circulation. 2021 Nov 16;144(20):1629-1645
• All: 1 reference(s)