Snhg15^tm1.1Nju
Targeted Allele Detail

Summary

• Symbol: Snhg15^tm1.1Nju
• Name: small nucleolar RNA host gene 15; targeted mutation 1.1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:6478876
• Synonyms: SAM^fl
• Gene: Snhg15 Location: Chr11:6475591-6478760 bp, - strand Genetic Position: Chr11, 4.37 cM
• Alliance: Snhg15^tm1.1Nju page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:291983
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A knockout-first allele was created by the insertion of the following elements into intron 2: an FRT site, splice acceptor sequence , IRES sequence, the lacZ gene, a loxP site a neomycin resistance gene, poly(A) signal sequence, a second FRT site and a second loxP site. A third loxP site was inserted into intron 4. This conditional ready allele was created through removal of the lacZ and neo cassettes by subsequent flp-mediated recombination, leaving exons 3 and 4 floxed. (J:291983)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Snhg15 Mutation: 9 strains or lines available

References

• Original: J:291983 Li Y, et al., Long noncoding RNA SAM promotes myoblast proliferation through stabilizing Sugt1 and facilitating kinetochore assembly. Nat Commun. 2020 Jun 1;11(1):2725
• All: 1 reference(s)