Tmem126b^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tmem126b^em1Cya
• Name: transmembrane protein 126B; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6478924
• Synonyms: Tmem126b^em1Cgen, Tmem126b-KO
• Gene: Tmem126b Location: Chr7:90118041-90125203 bp, - strand Genetic Position: Chr7, 50.6 cM, cytoband E1
• Alliance: Tmem126b^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• Exons 2-5 were targeted using CRISPR/Cas9 technology. (J:291866)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem126b Mutation: 17 strains or lines available

References

• Original: J:291866 Weihong C, et al., Transmembrane protein 126B protects against high fat diet (HFD)-induced renal injury by suppressing dyslipidemia via inhibition of ROS. Biochem Biophys Res Commun. 2019 Jan 29;509(1):40-47
• All: 1 reference(s)