Dpep3^em1Qsh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dpep3^em1Qsh
• Name: dipeptidase 3; endonuclease-mediated mutation 1, Qinghua Shi
• MGI ID: MGI:6488126
• Gene: Dpep3 Location: Chr8:106700152-106706051 bp, - strand Genetic Position: Chr8, 53.07 cM
• Alliance: Dpep3^em1Qsh page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 mediated recombination created a 2 bp deletion at nucleotides 32 and 33 (c.32-33del; p.Leu12Arg fs*52) resulting in a frameshift and premature stop at position 52. (J:289328)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dpep3 Mutation: 22 strains or lines available

References

• Original: J:289328 Xie Y, et al., The testis-specifically expressed Dpep3 is not essential for male fertility in mice. Gene. 2019 Aug 30;711:143925
• All: 1 reference(s)