Flacc1^em1Jw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Flacc1^em1Jw
• Name: flagellum associated containing coiled-coil domains 1; endonuclease-mediated mutation 1, Jeremy Wang
• MGI ID: MGI:6489264
• Gene: Flacc1 Location: Chr1:58696085-58735167 bp, - strand Genetic Position: Chr1, 29.15 cM, cytoband C2
• Alliance: Flacc1^em1Jw page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting of exon 2 produced a partial deletion of exon 2 and intron 2. Both the short and long isoforms are deleted. Western blot analysis confirmed the absent of protein expression. (J:298518)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Flacc1 Mutation: 35 strains or lines available

References

• Original: J:298518 Chotiner JY, et al., FLACC1 is testis-specific but dispensable for fertility in mice. Mol Reprod Dev. 2020 Nov 6
• All: 1 reference(s)