Ubr5^em2Mem
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ubr5^em2Mem
• Name: ubiquitin protein ligase E3 component n-recognin 5; endonuclease-mediated mutation 2, Marcy E MacDonald
• MGI ID: MGI:6489299
• Synonyms: Ubr5_del7
• Gene: Ubr5 Location: Chr15:37967572-38079098 bp, - strand Genetic Position: Chr15, 15.1 cM
• Alliance: Ubr5^em2Mem page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 7 bp. (J:298297)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ubr5 Mutation: 117 strains or lines available

References

• Original: J:298297 Loupe JM, et al., Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out. Hum Mol Genet. 2020 Nov 4;29(18):3044-3053
• All: 1 reference(s)