Gas5^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gas5^em1Gpt
• Name: growth arrest specific 5; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:6489537
• Synonyms: Gas5^em1Cd1152
• Gene: Gas5 Location: Chr1:160862171-160866109 bp, + strand Genetic Position: Chr1, 69.75 cM
• Alliance: Gas5^em1Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 2 to 5. (J:298688)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gas5 Mutation: 65 strains or lines available

References

• Original: J:298688 Li M, et al., GAS5 protects against osteoporosis by targeting UPF1/SMAD7 axis in osteoblast differentiation. Elife. 2020 Oct 2;9:e59079
• All: 1 reference(s)