Rab38^tm1.1Ics
Targeted Allele Detail

Summary

• Symbol: Rab38^tm1.1Ics
• Name: RAB38, member RAS oncogene family; targeted mutation 1.1, Mouse Clinical Institute
• MGI ID: MGI:6491324
• Gene: Rab38 Location: Chr7:88079481-88140780 bp, + strand Genetic Position: Chr7, 49.19 cM
• Alliance: Rab38^tm1.1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:293385
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The loxP-flanked exon 2 was removed via cre-mediated recombination. (J:293385)

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rab38 Mutation: 15 strains or lines available

References

• Original: J:293385 Aguilar A, et al., Combined deficiency of RAB32 and RAB38 in the mouse mimics Hermansky-Pudlak syndrome and critically impairs thrombosis. Blood Adv. 2019 Aug 13;3(15):2368-2380
• All: 1 reference(s)