Card11^em3Welu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Card11^em3Welu
• Name: caspase recruitment domain family, member 11; endonuclease-mediated mutation 3, Wei Lu
• MGI ID: MGI:6491990
• Gene: Card11 Location: Chr5:140858745-140986337 bp, - strand Genetic Position: Chr5, 79.42 cM
• Alliance: Card11^em3Welu page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a knock-out allele. (J:292926)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Card11 Mutation: 59 strains or lines available

References

• Original: J:292926 Wei Z, et al., Pathogenic CARD11 mutations affect B cell development and differentiation through a noncanonical pathway. Sci Immunol. 2019 Nov 29;4(41)
• All: 1 reference(s)