Caap1^em1Jcbs
Endonuclease-mediated Allele Detail

Summary

• Symbol: Caap1^em1Jcbs
• Name: caspase activity and apoptosis inhibitor 1; endonuclease-mediated mutation 1, Heinz Jacobs
• MGI ID: MGI:6492224
• Synonyms: C9orf82^ko
• Gene: Caap1 Location: Chr4:94388318-94445033 bp, - strand Genetic Position: Chr4, 43.32 cM, cytoband C5
• Alliance: Caap1^em1Jcbs page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed exons 2 through 4. (J:273282)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Caap1 Mutation: 15 strains or lines available

References

• Original: J:273282 Aslam MA, et al., Towards an understanding of C9orf82 protein/CAAP1 function. PLoS One. 2019;14(1):e0210526
• All: 1 reference(s)