Lrrc4b^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Lrrc4b^tm1Lex
• Name: leucine rich repeat containing 4B; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:6501150
• Gene: Lrrc4b Location: Chr7:44091911-44112775 bp, + strand Genetic Position: Chr7, 28.83 cM
• Alliance: Lrrc4b^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:276446
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• The beta-geo selection cassette replaced the coding sequence in the first coding exon. (J:276446)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrrc4b Mutation: 30 strains or lines available

References

• Original: J:276446 Lee H, et al., NGL-3 in the regulation of brain development, Akt/GSK3b signaling, long-term depression, and locomotive and cognitive behaviors. PLoS Biol. 2019 Jun;17(6):e2005326
• All: 1 reference(s)