Tuba1a^quas
Chemically induced Allele Detail

Summary

• Symbol: Tuba1a^quas
• Name: tubulin, alpha 1A; quasimodo
• MGI ID: MGI:6506270
• Gene: Tuba1a Location: Chr15:98847728-98851382 bp, - strand Genetic Position: Chr15, 55.29 cM
• Alliance: Tuba1a^quas page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: ENU mediated mutation created an A to T nonsense mutation creating a premature stop codon at amino acid 215 (p.R215*). (J:278765)

Disease models

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tuba1a Mutation: 15 strains or lines available

References

• Original: J:278765 Bittermann E, et al., Differential requirements of tubulin genes in mammalian forebrain development. PLoS Genet. 2019 Aug;15(8):e1008243
• All: 1 reference(s)