Bpgm^m1Pgrs
Chemically induced Allele Detail

Summary

• Symbol: Bpgm^m1Pgrs
• Name: 2,3-bisphosphoglycerate mutase; mutation 1, Philippe Gros
• MGI ID: MGI:6506869
• Synonyms: Bpgm^L166P
• Gene: Bpgm Location: Chr6:34453291-34482071 bp, + strand Genetic Position: Chr6, 15.01 cM
• Alliance: Bpgm^m1Pgrs page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: Genome-wide in vivo mutagenesis with N-ethyl N-nitrosourea (ENU) gave rise to this T-to-C mutation, which changes leucine codon 166 to a proline codon (p.L166P). (J:301620)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bpgm Mutation: 13 strains or lines available

References

• Original: J:301620 Xu G, et al., Bisphosphoglycerate Mutase Deficiency Protects against Cerebral Malaria and Severe Malaria-Induced Anemia. Cell Rep. 2020 Sep 22;32(12):108170
• All: 1 reference(s)