Kpna4^tm1Bdr
Targeted Allele Detail

Summary

• Symbol: Kpna4^tm1Bdr
• Name: karyopherin subunit alpha 4; targeted mutation 1, Michael Bader
• MGI ID: MGI:6507452
• Synonyms: Importin-alpha3^-
• Gene: Kpna4 Location: Chr3:68979554-69034425 bp, - strand Genetic Position: Chr3, 32.18 cM, cytoband E2
• Alliance: Kpna4^tm1Bdr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:302003
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 1 was replaced with a neomycin resistance gene cassette. (J:302003)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kpna4 Mutation: 30 strains or lines available

References

• Original: J:302003 Thiele S, et al., Cellular Importin-alpha3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection. Cell Rep. 2020 Apr 21;31(3):107549
• All: 1 reference(s)