Lypd8^tm1(cre)Ktak
Targeted Allele Detail

Summary

• Symbol: Lypd8^tm1(cre)Ktak
• Name: LY6/PLAUR domain containing 8; targeted mutation 1, Kiyoshi Takeda
• MGI ID: MGI:6508394
• Synonyms: Lypd8^{tm1(cre,Venus)Ktak}, Lypd8^venus
• Gene: Lypd8 Location: Chr11:58269869-58281365 bp, + strand Genetic Position: Chr11, 36.19 cM, cytoband B2
• Alliance: Lypd8^tm1(cre)Ktak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232706
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Recombinase, Reporter)
• Mutation: Insertion
• Lypd8^tm1(cre)Ktak expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lypd8 (MGI:1917413)

• Mutation details: Replacement of genomic fragment containing the third and fourth exons of the gene with a Cre recombinase gene, and internal ribosome entry site (IRES), a Venus gene and a neomycin-resistance gene cassette. (J:232706)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lypd8 (mouse) Summary of all recombinase alleles driven by Lypd8. Alliance mouse Lypd8 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lypd8 Mutation: 22 strains or lines available

References

• Original: J:232706 Okumura R, et al., Lypd8 promotes the segregation of flagellated microbiota and colonic epithelia. Nature. 2016 Apr 7;532(7597):117-21
• All: 1 reference(s)