Pkib^em1(cre)Fuki
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pkib^em1(cre)Fuki
• Name: protein kinase inhibitor beta, cAMP dependent, testis specific; endonuclease-mediated mutation 1, Izumi Fukunaga
• MGI ID: MGI:6508401
• Synonyms: Pkib-IRES-cre
• Gene: Pkib Location: Chr10:57508077-57617208 bp, + strand Genetic Position: Chr10, 29.22 cM
• Alliance: Pkib^em1(cre)Fuki page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Pkib^em1(cre)Fuki expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pkib (MGI:101937)

• Mutation details: Using CRISPR/cas9 technology an IRES-Cre sequence and a rabbit globin polyadenylation (rGpA) termination sequence were inserted just before the stop codon of the mouse Pkib gene. (J:315131)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pkib (mouse) Summary of all recombinase alleles driven by Pkib. Comparative matrix view of recombinase activities Alliance mouse Pkib gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pkib Mutation: 10 strains or lines available

References

• Original: J:315131 Koldaeva A, et al., Generation and Characterization of a Cell Type-Specific, Inducible Cre-Driver Line to Study Olfactory Processing. J Neurosci. 2021 Jul 28;41(30):6449-6467
• All: 1 reference(s)