Atg101^em1Nmz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Atg101^em1Nmz
• Name: autophagy related 101; endonuclease-mediated mutation 1, Noboru Mizushima
• MGI ID: MGI:6508992
• Synonyms: Atg101^-
• Gene: Atg101 Location: Chr15:101182182-101188855 bp, + strand Genetic Position: Chr15, 56.67 cM, cytoband F3
• Alliance: Atg101^em1Nmz page

Mutation origin

• Strain of Origin: C57BL/6JJcl

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• CRISPR/Cas9 genome editing technology was used to generate an insertion of an A residue in exon 2. (J:300057)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atg101 Mutation: 10 strains or lines available

References

• Original: J:300057 Morishita H, et al., Autophagy Is Required for Maturation of Surfactant-Containing Lamellar Bodies in the Lung and Swim Bladder. Cell Rep. 2020 Dec 8;33(10):108477
• All: 1 reference(s)