Prps1l1^em1Wyan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prps1l1^em1Wyan
• Name: phosphoribosyl pyrophosphate synthetase 1-like 1; endonuclease-mediated mutation 1, Wei Yan
• MGI ID: MGI:6509043
• Gene: Prps1l1 Location: Chr12:35034760-35036435 bp, + strand Genetic Position: Chr12, 15.64 cM, cytoband B2
• Alliance: Prps1l1^em1Wyan page

Mutation origin

• Strain of Origin: (FVB/NJ x C57BL/6J)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology deleted approximately 1 kb of the coding sequence and generated a knock-out allele. qPCR confirmed absence of mRNA in the testes. (J:301638)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prps1l1 Mutation: 15 strains or lines available

References

• Original: J:301638 Wang Z, et al., Prps1l1, a testis-specific gene, is dispensable for mouse spermatogenesis. Mol Reprod Dev. 2018 Oct;85(10):802-804
• All: 1 reference(s)