Fundc2^tm1Qim
Targeted Allele Detail

Summary

• Symbol: Fundc2^tm1Qim
• Name: FUN14 domain containing 2; targeted mutation 1, Qi Ma
• MGI ID: MGI:6509183
• Synonyms: FUNDC2-null
• Gene: Fundc2 Location: ChrX:74426005-74440065 bp, + strand Genetic Position: ChrX, 38.22 cM, cytoband A6
• Alliance: Fundc2^tm1Qim page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:301633
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 2 was replaced with a neomycin resistance gene cassette. (J:301633)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fundc2 Mutation: 6 strains or lines available

References

• Original: J:301633 Ma Q, et al., Mitochondrial PIP3-binding protein FUNDC2 supports platelet survival via AKT signaling pathway. Cell Death Differ. 2019 Jan;26(2):321-331
• All: 3 reference(s)