Ddx39b^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ddx39b^em1Cya
• Name: DEAD box helicase 39b; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6509428
• Synonyms: Ddx39b^em1Cgen
• Gene: Ddx39b Location: Chr17:35460722-35472683 bp, + strand Genetic Position: Chr17, 18.6 cM
• Alliance: Ddx39b^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 3 through 6. (J:299665)

Expression

In Mice Carrying this Mutation:

7 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ddx39b Mutation: 55 strains or lines available

References

• Original: J:299665 Xu Z, et al., Suppression of DDX39B sensitizes ovarian cancer cells to DNA-damaging chemotherapeutic agents via destabilizing BRCA1 mRNA. Oncogene. 2020 Nov;39(47):7051-7062
• All: 1 reference(s)