Cnot6l^em1Hyfn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cnot6l^em1Hyfn
• Name: CCR4-NOT transcription complex, subunit 6-like; endonuclease-mediated mutation 1, Heng-Yu Fan
• MGI ID: MGI:6509433
• Gene: Cnot6l Location: Chr5:96218192-96312030 bp, - strand Genetic Position: Chr5, 47.29 cM
• Alliance: Cnot6l^em1Hyfn page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Ten nucleotides located in exon 4 were deleted downstream of the translation start site. This deletion caused a reading frame shift, which created a premature stop codon. (J:270454)

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cnot6l Mutation: 45 strains or lines available

References

• Original: J:270454 Sha QQ, et al., CNOT6L couples the selective degradation of maternal transcripts to meiotic cell cycle progression in mouse oocyte. EMBO J. 2018 Dec 14;37(24)
• All: 4 reference(s)