Dcaf13^em2Hyfn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dcaf13^em2Hyfn
• Name: DDB1 and CUL4 associated factor 13; endonuclease-mediated mutation 2, Heng-Yu Fan
• MGI ID: MGI:6509579
• Synonyms: Dcaf13^fl
• Gene: Dcaf13 Location: Chr15:38976300-39010251 bp, + strand Genetic Position: Chr15, 15.42 cM
• Alliance: Dcaf13^em2Hyfn page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/Cas9 genome editing technology was used to insert LoxP sites to flank exon 2. (J:302700)

Expression

In Mice Carrying this Mutation:	31 assay results
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dcaf13 Mutation: 42 strains or lines available

References

• Original: J:302700 Zhang J, et al., Mammalian nucleolar protein DCAF13 is essential for ovarian follicle maintenance and oocyte growth by mediating rRNA processing. Cell Death Differ. 2019 Jul;26(7):1251-1266
• All: 4 reference(s)