Tarm1^tm1Yiw
Targeted Allele Detail

Summary

• Symbol: Tarm1^tm1Yiw
• Name: T cell-interacting, activating receptor on myeloid cells 1; targeted mutation 1, Yoichiro Iwakura
• MGI ID: MGI:6509631
• Gene: Tarm1 Location: Chr7:3535016-3551140 bp, - strand Genetic Position: Chr7, 2.04 cM
• Alliance: Tarm1^tm1Yiw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:301164
• Parent Cell Line: EGR-101 (ES Cell)
• Strain of Origin: C57BL/6NSlc

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with an EGFP gene and a neomycin resistance gene under the control of a PGK1 promoter. (J:301164)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tarm1 Mutation: 22 strains or lines available

References

• Original: J:301164 Yabe R, et al., TARM1 contributes to development of arthritis by activating dendritic cells through recognition of collagens. Nat Commun. 2021 Jan 4;12(1):94
• All: 1 reference(s)